Say there is one slightly loose limper (Ax K8s is fine to look at a flop) and you are mid-position with a hand like KQo, 88, QJs or something else that is worth a limp, raising 3x to 4x here is a fair play. The BB will be tempted to call and a 1/2 pot to 2/3 pot continuation bet should still have the desired effect.
Of course this doesn't work if your in a bad position to loose aggressive players sitting on your left. But if you have tighter players that are tending to respect your play, you may well buy position, or force a real hand to reveal itself.
Mixing up your AA or KK with slightly weaker raises especially if you showdown some winners with previous weaker holdings when making the same raise may even induce serious action preflop. This will hold more true from the almost good players with TT-QQ that now have a "read" on you.
Naturally you will be playing more post-flop holdem with this sort of weak raising, and you have to be comfortable in your read and working the board. With the smaller raises the pots should be managable and even if you have to give up a few of them, they should set you up for the big score. If you feel they are on to you or catching on to you, adjust and tighten back down before making this play TPGK will start seeing a showdown vs. your overpairs and then it is back to open season on raising more dubious hands for a bit.
I find I get too much respect happens to me playing online from the big stack and that these kinds of loose and aggressive plays often add enough doubt to my big hands that I wind up taking another stack. The worse that happens against opponents that respect me too much is that I take down a bunch of limps or a small to medium pot on the flop. If you are a good post flop player you shouldn't ever loose a massive pot unless your hand warrants it. It isn't easy switching to this style when you are first doing it, you are going to have to force yourself to pounce on pots and bet, even Doyle in SS says it was hard for him to adjust to playing this way.
Or it could be time to take some of your winnings on a Vegas trip
