I have moved up slowly on Party and have been playing the 100's for about a month. I find the play to be very similar to the 25's and actually think the play is more sane at the 50 level. My win rate is higher on the 100's than it was on the 50's.
I remember a play from last week that is very typical. A player ahead of me reraises to $10, I reraise to $40 basically announcing I have AA. The flop comes with an Ace and the player in front goes all-in with his QQ. I see things like this all the time.
Good luck, I know I am having fun!