First, estimate your advantage over your opponents. Suppose you are offered a near-coinflip with the better part of it, like
vs
. At what point would you refuse it? Like 55 vs AKs, or 33 vs AKs, I don't know, make a reasonable guess. Then you estimate the bankroll that you need for this. (it's better if you would precise which probability of going broke you accept in your estimation.)
I did some calculations and I'll post the results later, if there is some interest.
[2s] vs
[Ks]?
[Qs].